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Книга ISBN13 9783659537011 - Formulation and Evaluation of Fast Dissolving Oral Film (Ronak Gokani,Naisarg Pujara and Ramesh Parmar) в магазинах, библиотеках и электронных библиотеках с он-лайн чтением

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Название: Formulation and Evaluation of Fast Dissolving Oral Film
In the present study, formulation of Fast dissolving film containing antihistaminic drug Desloratadine was designed to achieve immediate release of drug from the dosage form, to increase therapeutic efficacy and to improve patient compliance in case of allergy. The combination of drug with suitable polymers such as HPMC E-5 and HPMC E-15 helps in providing quick onset of action. The basic aim of this work is to produce immediate release action of drug from the film. Fast dissolving film was prepared by solvent casting method using PEG 400 as plasticizer. A full factorial design was used to study the effect of HPMC E-5 and HPMC E-15 on disintegration time, thickness and folding endurance of the film. The responses were analyzed using ANOVA and by the polynomial equation. All the formulations were then evaluated for disintegration time, weight variation, and drug content and dissolution studies. Stability study shows that there was no significant change in physical appearance,...
Авторы: Ronak Gokani,Naisarg Pujara and Ramesh Parmar
Издательство: LAP Lambert Academic Publishing
Год: 2014
Местонахождение: OZON.ru
ISBN: 9783659537011


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10 января 2015 года: Запуск базы ISBN10 и ISBN13

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