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Книга ISBN13 9783844310696 - Formulation Strategies for dissolution enhancement of insoluble drugs (Rajnikant Patel,Madhabhai Patel and Natvarlal Patel) в магазинах, библиотеках и электронных библиотеках с он-лайн чтением

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Название: Formulation Strategies for dissolution enhancement of insoluble drugs
Dissolution is important parameter to achieve desired concentration of drug in systemic circulation for elicit pharmacological response. The formulation of poorly soluble drugs has been the subjects of much research, as approximately 40% of new chemical entities develop in pharmaceutical industries are insoluble in nature. In the present investigation drugs which are practically insoluble in gastric fluid and having high permeability through stomach were selected. The rational for selecting such type was “Drugs which are only permeable through stomach but due to its solubility limitation in gastric fluid they can not enter in to systemic circulation, further more gastric empting time is ranging form 30 mins to 2 hrs after this time drugs enter in to small intestine where they can soluble but can not permeable through its membrane due to its permeation limitation”. To improve dissolution of such drugs in stomach are challenging and rational. Attempts were made to prepare formulations...
Авторы: Rajnikant Patel,Madhabhai Patel and Natvarlal Patel
Издательство: LAP Lambert Academic Publishing
Год: 2011
Местонахождение: OZON.ru
ISBN: 9783844310696


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